Gene therapy protects against motor neuron disease in rats
The gene therapy approach allowed the non-mutated gene to be expressed in neurons and better support the transportation of proteins, preventing disease.
The gene therapy approach allowed the non-mutated gene to be expressed in neurons and better support the transportation of proteins, preventing disease.
Researchers mapped the genetic blueprints, appetites, and environments of more than 1,000 species of yeasts, building a family tree that illuminates how these single-celled fungi evolved over the past 400 million years.
Size doesn’t matter when it comes to genome sequencing in the animal kingdom, as a team of researchers at the Morgridge Institute for Research recently illustrated when assembling the sequences for two new reference genomes — one from the world’s largest mammal and one from one of the smallest.
While some people may first associate daddy longlegs with well, their legs, researchers from the Department of Integrative Biology have been especially focused on the arachnids’ eyes and what they can tell us about their evolution.
The humble fruit fly is one of the most thoroughly studied animals on the planet and new insights continue to be revealed about the fly’s evolution thanks to centuries-old DNA.
The midbody’s involvement in cell signaling and stimulating cell proliferation has been investigated before, but UW researchers wanted to look inside the midbody remnants to learn more.
Using DNA extracted from fecal samples, researchers at UW–Madison and the University of Texas at Austin are better able to understand the reproductive patterns of the endangered northern muriqui.
New research reveals how diversity within its genome has allowed the pest to quickly evolve resistance to nearly anything humans have thrown at it.
Researchers argue that such advanced technologies demand more robust and thoughtful public engagement if they are to be harnessed to benefit society without crossing ethical lines.
Renata Laxova focused on intellectual and developmental disabilities, prenatal diagnosis of birth defects, cancer genetics, and — above all — the relationships between medical professionals and patients.
A gene that cured a man of HIV a decade ago has been successfully added to developing monkey embryos in an effort to study more potential treatments for the disease.
“She lived life to the fullest and did so unapologetically. It didn’t matter that she had spinal muscular atrophy. It didn’t matter that she was a Black woman in a society that didn’t fight for her. She was still going to fight for the life she deserved.”
Work by Brian Parks and collaborators provides a new target for understanding the genetic risk of high cholesterol, which is linked to heart disease.
The edited cells are a step toward studying the degenerative neurological disorder in a primate model, which has proven elusive.
The predictive tool is a boon for researchers studying how cells control the activity of genes, helping explain how cells achieve their key functions and how they go haywire, as happens in diseases such as cancer.
A new trove of genomic data could allow researchers to develop novel features in fermented beverages, an industry worth hundreds of billions of dollars.
Ahna Skop, a professor, artist and advocate for underrepresented students, has been selected for an initiative to further women in science by the American Association for the Advancement of Science.
Genomic research is at the forefront of modern biological investigation. UW–Madison’s strong status in this rapidly evolving field has led to creation of the Center for Genomic Science Innovation.
Scientists in the University of Wisconsin–Madison Department of Biochemistry are blasting E. coli bacteria with ionizing radiation once a week to watch evolution happen in real time as the bacteria become radiation resistant.
Behind the world’s most popular alcoholic beverage is a yeast adapted to the cold. New research has shown how modern lager yeast adopted the cold-loving and sugar-hungry traits essential to their success.