Tag Stem cells
This is the first in a series of four videos about stem cell research at UW–Madison: how it started, what it's achieved, and where it's headed. Catch up on what's happened since James Thomson's prescient prediction that stem cells "will change medicine, period."
At least 10 Wisconsin businesses fundamentally depend, in one way or another, on pluripotent stem cells. In our continuing series, we profile each of these companies, spun off from UW–Madison research.
Ashton, a leading UW–Madison stem cell scientist whose lab develops novel tissue engineering methods to derive brain and spinal cord tissues from human pluripotent stem cells, will assume a leadership position with the Stem Cell and Regenerative Medicine Center.
Beginning with just five cell lines derived from surplus embryos donated by patients who had finished undergoing fertility treatments, human stem cell science has mushroomed from just a few isolated labs to a burgeoning global industry and launched the new field of regenerative medicine.
When Kaivalya Molugu was considering graduate schools, she knew she was interested in stem cell research, but she had to decide where to apply. The answer soon became clear: the place where it all began.
In Wisconsin, key to growing and empowering the community of stem cell researchers is the UW–Madison Stem Cell and Regenerative Medicine Center.
Responsible science is almost always a slow, grueling process, but 20 years after James Thomson derived the first human embryonic stem cell lines, experts in the field of stem cell and regenerative medicine feel more optimistic than ever.
“If UW–Madison is the birthplace of human embryonic stem cells, then the Primate Research Center is the cradle,” says Marina Emborg, director of the center's Preclinical Parkinson's Research Program.
More than 250 million people, mostly in Africa and Asia, have schistosomiasis, which kills an estimated 280,000 each year. “We don’t get that many aha! moments in our lives as scientists,” says a researcher. “This was one of them.”
UW–Madison has doctors willing to guide the studies that will make or break cell therapy companies. “If you are a clinician, you need a pioneer spirit to do something that has never been done before,” Jacques Galipeau says, “and there are already many like that here.”
A UW–Madison study showed that the absence of the protein FMRP can unbalance critical molecular processes within adult brain cells and lead to the neural and cognitive changes seen in fragile X.
The Morgridge Rural Summer Science Camp has allowed more than 500 high-academic achievers from across the state to spend a week learning from leaders in stem cell research, a field that UW–Madison helped make famous.
Speakers at the annual Wisconsin Stem Cell Symposium will discuss clinical trials involving stem cells, safety considerations and the regulatory environment under which ongoing stem cell work takes place.
A regenerative biology team at the Morgridge Institute for Research led by Dave Vereide unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.