Tag Stem cells
New tool provides researchers with improved understanding of stem cell aging in the brain
By identifying and decoding these autofluorescence signatures, the researchers have developed a tool that can aid in studying adult neurological diseases and aging, but potentially also expand beyond neuroscience.
Stem cell technology developed at UW–Madison leads to new understanding of autism risks
Ashton says researchers using technologies like the RosetteArray are finding that the risk factors for autism spectrum disorder are boiling down to a couple of core pathways, that seem to have roles very early in human brain development, which is helpful information as researchers work on treatments.
Scientists produce human norepinephrine neurons from stem cells, with significant implications for researching diseases like Alzheimer’s and Parkinson’s
Researchers have identified a protein that is key to the development of a type of brain cell believed to play a role in disorders like Alzheimer’s and Parkinson’s diseases and used the discovery to grow the neurons from stem cells for the first time.
Combining cell types may lead to improved cardiac cell therapy following heart attack
A new study from researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan points to an improved method for regenerating heart muscle following a heart attack.
Discovery reveals mitochondria as potential treatment target for fragile X syndrome
The results fundamentally change how scientists understand the developmental origins of fragile X syndrome and suggest a potential treatment for brain cells damaged by the dysfunction.
Improved understanding of early spinal cord development paves the way for new treatments
Researchers at the University of Wisconsin–Madison are developing the means to turn stem cells into a wide range of specific types of spinal cord neurons and cells in the hindbrain — the critical nexus between the spinal cord and the brain — paving the way for improved prevention and treatment of spinal cord disease.
Creating stem cells from minipigs offers promise for improved treatments
A new study from Wan-Ju Li's lab in the UW–Madison Stem Cell & Regenerative Medicine Center advances research into reparative osteoarthritis therapies using stem cells derived from the ears of miniature pigs.
New study allows researchers to more efficiently form human heart cells from stem cells
The heart muscle cells, according to the UW–Madison Stem Cell & Regenerative Medicine Center, could be useful for cardiac repair, regeneration and cell therapy.
A science trailblazer retires: Stem cell researcher James Thomson’s legacy changed the future of biology
After more than 30 years with UW–Madison and 12 years with the Morgridge Institute for Research, Thomson has announced plans to retire in July.
Mouse study may help doctors choose treatments for leukemia patients
By exploring the ways mice responded, researchers hope to gain an understanding of the sorts of human health issues that may bring on a case of this life-threatening form of cancer.
Stem cell project to create new model to study brain development and Down syndrome
The research is funded through an $11 million Transformative Research grant from the National Institutes of Health, which supports exceptionally innovative or unconventional research projects with the potential to advance their field.
Individualized brain cell grafts reverse Parkinson’s symptoms in monkeys
UW researchers say the stem cell treatment is an "extremely powerful" step toward a treatment for millions of human Parkinson’s patients.
UW–Madison leads DoD-funded effort to restore vision to injured service members and people with disease
The technology will be based on a system in which human induced pluripotent cells are used to generate light-responsive eye cells called photoreceptors along with the cells that support them.
Multiple gene edits and computer simulations could help treat rare genetic diseases
Research in biomedical engineer Kris Saha's lab efficiently corrected multiple mutations responsible for Pompe disease, advancing the CRISPR genome-editing field.
Stem cells can repair Parkinson’s-damaged circuits in mouse brains
UW neuroscientists led by Su-Chun Zhang found that neurons derived from stem cells can connect with native neurons and restore motor functions. But more research is needed to translate the findings from mice to people.
Shared protein fingerprint could simplify treatment of common inherited heart disease
The findings reinforce that genetic mutations aren’t always enough to explain diseases, says Ying Ge, a professor of cell and regenerative biology and chemistry at UW–Madison who headed the new study.
New tool for assessing heart muscle cells helps unlock their potential
Researchers have created a way to study how heart cells made from stem cells organize themselves into muscle that could be used to screen drugs or develop therapies for heart disease.
Moving beyond hype: Could one-two treatment restore damaged heart muscle?
UW-Madison researchers hope a combination of two cutting-edge approaches would use a fabric-like material to prevent “wash-out” and successfully implant cardiomyocytes to damaged hearts.
Rural Summer Science Camp expands opportunities, curriculum in its 13th year
The camp, where rural high school students and teachers take a deep dive into science research, is offering a third week this July thanks to support from the National Science Foundation.
A new way to wind the development clock of cardiac muscle cells
A study published in the journal Stem Cells describes a new and unexpected way to accelerate the maturation of induced pluripotent stem cells into cardiac muscle cells.