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Tag Animal research

New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice

January 19, 2023

UW researchers have found a way to move gene therapies through the blood-brain barrier, a crucial step for brain-wide CRISPR treatments of disorders like Alzheimer's and Parkinson's disease.

Probiotic ‘backpacks’ show promise for treating inflammatory bowel diseases

November 11, 2022

UW researchers demonstrate just how much promise some well-equipped bacteria hold for improved inflammatory bowel disease treatments.

Brain-gut connection may reveal way to prevent cocaine addiction

November 10, 2022

Cocaine disrupts the balance of microbes in the guts of mice, part of a cycle of waxing and waning neurochemicals that can enhance the drug’s effects in the brain. But the same chemicals may also be harnessed to prevent addiction, according to new research.

Study shows differences between brains of primates — humans, other apes and monkeys — are small but significant

November 8, 2022

The cellular differences between these species may illuminate steps in their evolution and how those differences can be implicated in disorders, such as autism and intellectual disabilities, seen in humans.

Wild primate virus has pandemic potential should it jump the species barrier, shows study

October 28, 2022

New research demonstrates the potential for a family of viruses in African primates to jump the species barrier to humans.

Monitoring an invasion: Where are jumping worms now?

October 7, 2022

Invasive jumping worms threaten soil health in Wisconsin, including in Dane County where the population has infested the University of Wisconsin–Madison Arboretum. Brad Herrick leads crews of volunteers to survey for the worms so that researchers can study their movements and possibly find ways to halt their spread.

New study allows scientists to test therapeutics for rare disease affecting young children

September 26, 2022

The team used CRISPR gene editing technology to create in rat embryos the mutations that lead to HSP. This allowed them to study how the disease progresses from early development and monitor the progression of symptoms after birth.

Avian influenza persists as migration peaks

September 19, 2022

The persistence of highly pathogenic avian influenza in wild and domestic birds through the summer months points to a likely rise in cases this fall, according to Wisconsin Veterinary Diagnostic Laboratory Director Keith Poulsen.

Creating stem cells from minipigs offers promise for improved treatments

September 15, 2022

A new study from Wan-Ju Li's lab in the UW–Madison Stem Cell & Regenerative Medicine Center advances research into reparative osteoarthritis therapies using stem cells derived from the ears of miniature pigs.

Chancellor Mnookin tours dairy farm, highlights research efforts

September 13, 2022

The visit to two dairy farms highlighted the Dairy Innovation Hub, a partnership that conducts research and offers support to Wisconsin's dairy industry.

How a small, unassuming fish helps reveal gene adaptations

September 8, 2022

New UW–Madison research sheds light on the genetic basis by which stickleback populations inhabiting ecosystems near each other developed a strong immune response to tapeworm infections, and how some populations later came to tolerate the parasites.

UW Veterinary Care offers rabbit vaccine against highly contagious, fatal disease

May 5, 2022

The clinic is one of about a dozen animal hospitals in the state to offer the vaccine and part of a growing effort nationally to encourage rabbit owners to seek vaccination.

Biodegradable gel boosts immune system’s attack on several cancers in mice

April 6, 2022

The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate T cells so they can attack cancer.

Canine TV preferences could lead to answers in protecting dogs’ eyesight

March 23, 2022

A UW study is asking dog owners what their pets like to watch — a nontrivial question that could lay the groundwork for developing better canine eye tests.

In animal studies, maternal sleep apnea risks ‘constellation of deficits’ in male offspring

February 28, 2022

The findings offer guidance to physicians to help mitigate risk to children of a significant number of expectant parents.