Tag Animal research
A gene that cured a man of HIV a decade ago has been successfully added to developing monkey embryos in an effort to study more potential treatments for the disease.
A study shows that the mutant virus is more easily transmitted and grows better within hosts, likely aiding its dominance. The mutation, researchers say, should not interfere with the effectiveness of vaccines against the virus.
Neither of the new viruses is known to infect people, but the findings reinforce the important work scientists are undertaking to study the effects of a changing environment on human and animal diseases.
UW neuroscientists led by Su-Chun Zhang found that neurons derived from stem cells can connect with native neurons and restore motor functions. But more research is needed to translate the findings from mice to people.
Researchers believe the same approach can be applied to several other respiratory pathogens, including the novel coronavirus that causes COVID-19.
Leaders and staff at UW–Madison, including people who care for and provide oversight of our animals, take seriously our responsibility to care for animals in research.
The trials center around an “antibody cocktail” called REGN-COV2, which was created by the New York-based pharmaceutical company Regeneron.
UW–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine that has advanced to clinical trials.
The animals are useful to researchers trying to understand SARS-CoV-2 and in the evaluation of vaccines, treatments and drugs against the disease it causes.
Researchers advise that people with symptoms avoid contact with cats, and cat owners should keep their pets indoors to limit contact with other people and animals.
Researchers hope to better understand how coronaviruses enter cells, spread, and cause varying immune responses in different individuals.
Work by Brian Parks and collaborators provides a new target for understanding the genetic risk of high cholesterol, which is linked to heart disease.
Although the global surge in demand has made it more difficult in many places, WSLH’s colleagues at the university have pitched in to keep testing available in Wisconsin.
Refinement of the CoroFlu vaccine concept and testing in laboratory animal models at UW–Madison is expected to take three to six months. CoroFlu could be in human clinical trials by fall, 2020.
The cellular sleight of hand, says biomolecular chemist Feyza Engin, may also suggest ways to prevent other diseases in which the immune system targets the body’s own cells.
A UW–Madison study provides a new avenue of research for understanding and potentially preventing the development of asthma, which affects 25 million Americans.
A small amount of electricity delivered at a specific frequency to a particular point in the brain will snap a monkey out of even deep anesthesia, pointing to a circuit of brain activity key to consciousness and suggesting potential treatments for debilitating brain disorders.
Within the next few weeks, an interdisciplinary team of UW scientists hopes to begin studies of 2019-nCoV to "erect more barriers to prevent this sort of thing from happening in the future.”
If they are shown to work as well in the body as they do in pharmacy Professor Seungpyo Hong's lab, the nanoparticles might provide an effective and more affordable way to fight cancer.
As Super Bowl LIV airs Sunday, Feb. 2, Scout will appear alongside members of the school's faculty and staff who have been part of the 7-year-old golden retriever’s cancer treatment journey.