Researchers in the School of Pharmacy, led by Quanyin Hu, have developed a system that can keep probiotic bacteria alive in the lower intestine long enough to help treat or prevent colitis in a mouse model of the disease.
The technology, developed by UW–Madison Professor Weiping Tang and colleagues in the School of Pharmacy, could produce entirely new kinds of drugs.
“It’s a win-win,” says pharmacy student Maggie Hoernke. “We get practice educating patients and administering the vaccine, and we also get to help out the public.
The findings add to a growing understanding of how the immune system can recognize drugs and influence their effects in the body, which may ultimately support the production and delivery of a vaccine that reduces the harm of opioid abuse.
He says CIPE’s focus on team-based learning and practice will provide UW–Madison health sciences students purposefully-designed interprofessional learning and socialization, both of which will better prepare them for team-based practice.
A team of UW–Madison researchers has been awarded a patent for a method to synthesize acetaminophen — the active ingredient in Tylenol — from a natural compound derived from plant material.
Researchers drew inspiration from easy-to-read weather maps and consulted with doctors to provide guidance at a glance of the likelihood a pathogen will respond to a particular drug in different parts of the state.
“We are building a preclinical drug discovery organization,” says WARF Therapeutics Director Jon Young, who has worked in drug development at Merck Research Laboratories, Regulus Therapeutics and Celgene.
A UW–Madison program aims to give African Americans in Milwaukee strategies to maintain healthy lifestyles that will help prevent and/or manage Type 2 diabetes.
Jason Peters and colleagues have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.
A simple blood test could help doctors understand what medication might work best for patients at the start of their treatment, according to new UW–Madison research.
UW–Madison has doctors willing to guide the studies that will make or break cell therapy companies. “If you are a clinician, you need a pioneer spirit to do something that has never been done before,” Jacques Galipeau says, “and there are already many like that here.”
Researchers in pharmacy and bacteriology say their discovery would not have been possible without a cross-college collaboration going back nearly a decade.
To help physicians choose the best antibiotic first, researchers in the School of Pharmacy and the State Cartographer's Office are drawing inspiration from the weather.