Tag Animal research
New imaging agent provides better picture of the gut
A multi-institutional team of researchers has developed a new nanoscale agent for imaging the gastrointestinal (GI) tract. This safe, noninvasive method for assessing the function and properties of the GI tract in real time could lead to better diagnosis and treatment of gut diseases.
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Writing today (July 14, 2014) in the journal Nature Communications, a group led by University of Wisconsin–Madison stem cell researcher Igor Slukvin reports the discovery of two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood.
Chemical strategy hints at better drugs for osteoporosis, diabetes
By swapping replacement parts into the backbone of a synthetic hormone, UW–Madison graduate student Ross Cheloha and his mentor Sam Gellman, along with collaborators at Harvard Medical School, have built a version of a parathyroid hormone that resists degradation in laboratory mice. As a result, the altered hormone can stay around longer - and at much higher concentration, says Gellman, professor of chemistry at the UW.
Genes found in nature yield 1918-like virus with pandemic potential
An international team of researchers has shown that circulating avian influenza viruses contain all the genetic ingredients necessary to underpin the emergence of a virus similar to the deadly 1918 influenza virus.
Foxes among Badgers: A family of foxes makes its home on campus
There are foxes on campus. Big ones and little ones, a new family that started this spring.
Hair from infants gives clues about their life in the womb
Like rings of a tree, hair can reveal a lot of information about the past.
Monkey caloric restriction study shows big benefit; contradicts earlier study
The latest results from a 25-year study of diet and aging in monkeys shows a significant reduction in mortality and in age-associated diseases among those with calorie-restricted diets. The study, begun at the University of Wisconsin–Madison in 1989, is one of two ongoing, long-term U.S. efforts to examine the effects of a reduced-calorie diet on nonhuman primates.
Study suggests potential association between soy formula and seizures in children with autism
A University of Wisconsin–Madison researcher has detected a higher rate of seizures among children with autism who were fed infant formula containing soy protein rather than milk protein.
Famed Milwaukee County Zoo orangutan’s death caused by strange infection
Mahal, the young orangutan who became a star of the Milwaukee County Zoo and an emblem of survival for a dwindling species, led an extraordinary life. It turns out, the young ape died an extraordinary death, too.
A shift in stem cell research
A team of engineers at the University of Wisconsin–Madison has created a process to improve the creation of synthetic neural stem cells for use in central nervous system research.
Researchers Link Protein With Breast Cancer’s Spread to the Brain
A cancer-research team at the University of Wisconsin–Madison has identified a protein that may be a major culprit when breast cancer metastasizes to the brain.
Estrogen: Not just produced by the ovaries
A University of Wisconsin–Madison research team reports today that the brain can produce and release estrogen - a discovery that may lead to a better understanding of hormonal changes observed from before birth throughout the entire aging process.
Rare disease yields clues about broader brain pathology
Alexander disease is a devastating brain disease that almost nobody has heard of — unless someone in the family is afflicted with it. Alexander disease strikes young or old, and in children destroys white matter in the front of the brain. Many patients, especially those with early onset, have significant intellectual disabilities.
Impulsivity, rewards and Ritalin: monkey study shows tighter link
Even as the rate of diagnosis has reached 11 percent among American children aged 4 to 17, neuroscientists are still trying to understand attention deficit hyperactivity disorder (ADHD). One classic symptom is impulsivity — the tendency to act before thinking.
Vet med scientists find better, safer treatments for hoof disease in cattle
For almost 40 years, digital dermatitis has plagued cattle throughout the world. Also called heel warts, these painful hoof lesions limit the amount of time cows can stand and feed, which can hinder animal welfare and food production. The disease can be found on almost every beef and dairy farm in North America, so it has a significant economic impact on those industries in the United States.
H5N1 bird flu genes show nature can pick worrisome traits
In a study published today (Oct. 23, 2013) in Nature Communications, an international team of researchers shows how evolution can favor mutations that make avian flu more transmissible in mammals.
Biomanufacturing center takes central role in developing stem-cell therapies
Developing a new drug takes enormous amounts of time, money and skill, but the bar is even higher for a promising stem-cell therapy. Many types of cells derived from these ultra-flexible parent cells are moving toward the market, but the very quality that makes stem cells so valuable also makes them a difficult source of therapeutics.