Tag Health & medicine

Fragile X protein may play role in Alzheimer’s disease

February 13, 2007

A brain afflicted by severe Alzheimer's disease is a sad sight, a wreck of tangled neural connections and organic rubble as the lingering evidence of a fierce internal battle. A new study has now uncovered an unexpected link between this devastating neural degeneration and a protein whose absence causes a different neurological disease - the inherited mental retardation disorder called fragile X syndrome.

Dieting meets DNA: Nutrition gets personal in new studies

November 15, 2006

Ushering nutritional science into the biotech age, UW–Madison researchers are exploring the complex interactions between food and genes to uncover new modes of disease prevention, drug development and, eventually, personalized diet advice tailored to one’s DNA.

Illuminating Alzheimer’s: Research sheds light on creatine’s presence in brain

December 21, 2005

A team of Canadian and American scientists working at the UW–Madison Synchrotron Radiation Center reports the first-ever finding of elevated levels of creatine — the newly discovered agent of Alzheimer's disease - in brain tissue.

Protective protein may hold key to halting progression of neurological diseases

January 11, 2005

Patients who suffer from neurological diseases such as Huntington's disease, Parkinson's, Lou Gehrig's disease (ALS) and Alzheimer's disease have dramatically different symptoms. An Alzheimer's patient, for instance, will lose memory and cognitive function, while an ALS sufferer will gradually lose motor control.

Discovery may halt progression of Alzheimer’s

September 2, 2004

In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer's disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease. The findings appear in the current issue of The Journal of Neuroscience.

ES cell model could provide clues to causes, cures for diabetes

July 28, 2003

By studying embryonic stem cells from a mouse, researchers at UW–Madison have identified a potential model system for elucidating the stages of normal pancreatic development, as well as for developing a much-needed source of insulin-producing cells for the millions of people who need them to treat their diabetes.

Obesity, smoking and inactivity top health concerns

January 14, 2003

In a recent informal poll of UW Health primary care experts, obesity, smoking and inactivity were ranked the health problems most patients need to take seriously. Depression, diabetes and hypertension were not far behind. The good news: tackling even one of these problems will likely improve your health in several areas.

Subtract a gene and feasting mice add no fat

August 13, 2002

Scientists have created an animal that can eat a rich, high-fat diet without adding weight or risking the complications of diabetes

New Alzheimer’s study to focus on children

January 29, 2002

As the number of new Alzheimer's cases balloons to a projected 14 million by 2050, the Medical School is establishing the nation's first comprehensive research study of children of people with Alzheimer's disease.

Disarming Alzheimer’s Toxic Proteins

April 14, 1997

A new study of the proteins that may be responsible for the brain lesions associated with Alzheimer's disease promises a new understanding of its underlying cause, and may someday yield new treatments for the devastating and deadly disease.