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Tag Drugs

UW-Madison team developing ‘tissue chip’ to screen neurological toxins

September 23, 2014

A multidisciplinary team at the University of Wisconsin–Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals that may harm human development. Read More

University spinoff aims to hit the mark precisely with brain-scanning tool

August 20, 2014

As brain surgeons test new procedures and drugs to treat conditions ranging from psychiatric disorders to brain cancer, accuracy is becoming an ever-greater issue. Read More

Chemical strategy hints at better drugs for osteoporosis, diabetes

June 16, 2014

By swapping replacement parts into the backbone of a synthetic hormone, UW–Madison graduate student Ross Cheloha and his mentor Sam Gellman, along with collaborators at Harvard Medical School, have built a version of a parathyroid hormone that resists degradation in laboratory mice. As a result, the altered hormone can stay around longer - and at much higher concentration, says Gellman, professor of chemistry at the UW. Read More

Lighting up the lab: Team harnesses light for controlled chemical reaction

April 24, 2014

When chemist Tehshik Yoon looks out his office window, he sees a source of energy to drive chemical reactions. Plants “learned” to synthesize chemicals with sunlight eons ago; Yoon came to the field a bit more recently. But this week, in the journal Science, he and three collaborators detail a way to use sunlight and two catalysts to create molecules that are difficult to make with conventional techniques — a finding that may eventually have implications for drug making and materials science. Read More

Model virus structure shows why there’s no cure for common cold

October 28, 2013

In a pair of landmark studies that exploit the genetic sequencing of the “missing link” cold virus, rhinovirus C, scientists at the University of Wisconsin–Madison have constructed a three-dimensional model of the pathogen that shows why there is no cure yet for the common cold. Read More