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Research may yield better laxative

December 13, 2001

Along with the aches and pains of aging often comes constipation. Though over-the-counter fiber supplements that contain psyllium seed husks can help keep us regular, many taste unpleasant. While the supplements mixed into drinks taste gritty, those incorporated into foods tend to gel in the mouth. A recent development made by nutritional scientists at could lead to a more pleasing product.

UW–Madison researchers Judith Marlett and Milton Fischer identified the active agent of psyllium seed husks — the main ingredient in supplements such as Metamucil — and developed a concentrated source of fiber. Their studies show that this concentrated form is just as effective at producing regularity.

Bulk-fiber, psyllium seed husks act like sponges as they move through the digestive system. They collect water and waste, making stool softer and bulkier. Their special gelatinous quality makes stool slick and easier to pass. Studies have proven that just seven grams of fiber from these husks a day, along with a diet low in saturated fat, lower blood cholesterol levels and possibly reducing the risk of heart disease and stroke.

Achieving these results, however, requires ingesting tablespoons of husks. Such large doses may be hard to take, especially for those who have difficulty swallowing — a problem that sometimes crops up with age.

The UW–Madison researchers’ concentrated form, which also lowers cholesterol levels, could lead to smaller doses, perhaps someday even in the form of tablets or capsules, says Marlett. “It’s really going to be a nice product once somebody develops it.”

Tags: research