Taking advantage of the unique biochemical properties of protein fragments, their tool uses less expensive, more efficient, off-the-shelf chemical compounds to help identify sites where proteins were cut.
Biochemists at UW–Madison have developed a tool to control how certain proteins move in mammalian cells, a discovery that has multiple potential uses for treating or studying diseases by engineering specific cellular activities or studying cellular activity in a living organism.
A new art installation preserves some of the wood from an elm tree fondly known as Elmer, which stood in the Biochemical Sciences Complex Plaza until it succumbed to Dutch elm disease in 2018. The hanging piece was installed in the Biochemistry Sciences Building atrium in October 2023.
The discovery could eventually help researchers better understand and develop new treatments for diseases like cancer, diabetes and those that cause immune dysfunction.
Many cancers are the result of corrupted signaling pathways, and a more nuanced understanding of those pathway disruptions may be a key step in developing targeted treatments.
A curlicue RNA molecule dubbed a pUG can silence gene expression in roundworms, according to new findings. Researchers are using what they've learned to study human pUGs and their role in our own gene expression.
The research provides insight into how a human cell preserves the integrity of its DNA through repeated cell division.